
Islas Secas Vacations from $716
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
Better together
Save up to $1,045 when you book a flight and hotel together*
Find the right fit
With over 300,000 hotels worldwide, it's easy to create a perfect package
Rest easy
Plan, book, and manage your trip all in one place
The Latest Islas Secas vacation packages
Price found within the past 48 hours. Click for updated prices.

Yoo Apartamento
Bella Vista
Price was $979, price is now $716 per person
$716
per person
Oct 30 - Nov 4
found 20 hours ago
Roundtrip non-stop flight included
New York (NYC) to Panama City (PTY)
10/10 Exceptional! (5 reviews)
The location and view are amazing! This is a great place to stay.
Reviewed on Jan 14, 2025

Central Hotel Panama Casco Viejo
Casco Viejo
Save 100% on your flight
Price was $1,628, price is now $1,001 per person
$1,001
per person
Nov 3 - Nov 8
found 1 day ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
9/10 Wonderful! (974 reviews)
Everyone was very friendly and super helpful. Location was super convenient. Will definitely stay again.
Reviewed on Aug 20, 2025

Villa Botero By Casa Mojito B&B
Price was $1,087, price is now $765 per person
$765
per person
Oct 9 - Oct 14
found 1 day ago
Roundtrip non-stop flight included
New York (NYC) to Panama City (PTY)
9.8/10 Exceptional! (60 reviews)
Host was excellent. Great communication and very helpful. The rooms were nice and great value.
Reviewed on Apr 18, 2025


Hotel Riu Plaza Panama
Bella Vista
Price was $1,016, price is now $738 per person
$738
per person
Nov 3 - Nov 8
found 1 day ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
9/10 Wonderful! (4,176 reviews)
My husband and I stayed at this property to celebrate our 12yr anniversary. The property, customer service and suite were amazing. The hotel is walkable to any great restaurants and shops. Additionally, the sushi and drinks at the lobby bar were delicious as well. I would definitely stay here again.
Reviewed on Aug 22, 2025
Don't see what you're looking for?
See all available trips from Columbus to Islas Secas
View all tripsIslas Secas Hotel Deals

Bocas del Mar Hotel
Road to Boca Chica, Boca Chica, Chiriqui
$192 nightly
The price is $212 total per night from Aug 27 to Aug 28
$212 total
Aug 27 - Aug 28
Total with taxes and fees
9.6/10 Exceptional! (214 reviews)
Visit to Boca Chica
"Great stay at the hotel, wonderful service and great views. Wonderful place for enjoying the ocean views and activities."
Reviewed on Mar 3, 2025

Isla Palenque Member of the Cayuga Collection
Isla Palenque, Chiriqui, Boca Chica
"Absolutely incredible time!"
Reviewed on May 7, 2024

El Regalo Resort
RB048 Calle Syah Johan, Boca Chica, Chiriqui
$130 nightly
The price is $143 total per night from Aug 24 to Aug 25
$143 total
Aug 24 - Aug 25
Total with taxes and fees
9.8/10 Exceptional! (23 reviews)
"Food was really good, bed very confortable and nice quiet place"
Reviewed on Aug 10, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
More vacations you might like
Frequently asked questions
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.